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If fatigue proves intolerable despite optimization of nutrition, hydration, and lifestyle factors, your provider may consider adjusting your tirzepatide dose, slowing the titration schedule, or exploring alternative treatment options

Phentermine: Not approved for long-term use due to potential for abuse and side effects

Stomach ulcers or kidney disease Avoid ibuprofen if you have a history of stomach ulcers or kidney problems, as it can cause serious internal bleeding or sudden kidney failure

Key monitoring parameters include: Blood glucose levels : Continue regular self-monitoring of blood glucose as advised by your diabetes team