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A study in mice revealed that betaine can restore the function of adipose tissue and sensitivity to insulin, and these effects may be attributed to the alleviation of endoplasmic reticulum stress (Reference Wang, Yao and Pini34)

Glutathione peroxidase activity is neuroprotective in models of Huntington's disease

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Immunoblotting Cells or tissues were lysed with RIPA lysis buffer (150 mM NaCl, 100 mM Tris, 5 mM EDTA, and 1% Triton-100) supplemented with 0.1 mmol/L PMSF (Beyotime, Shanghai, China, #ST505) and 1 mmol/L protease inhibitor cocktail (MCE, Monmouth Junction, NJ, #HY-K0010)