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Different reconstitution volumes produce different concentrations from the same vial: 50mg vial + 2ml water = 25mg/ml (very concentrated) 50mg vial + 2.5ml water = 20mg/ml (concentrated) 50mg vial + 5ml water = 10mg/ml (standard) 50mg vial + 10ml water = 5mg/ml (dilute) Higher concentrations require smaller injection volumes but may exceed solubility limits for some peptides

Volume = 1 mg / 5 mg/ml = 0.2 ml Challenge here: 0.2 ml is very difficult to measure with a standard syringe

This is one of the most common reactions our collaborating dietitian and exercise physiologist, Chantelle, sees in our clinic

Additionally, vomiting or diarrhoea can increase electrolyte loss