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doi: 10.1038/s41401-021-00727-z 133 TianY.WangW.XuL.LiH.WeiY.WuQ.et al

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The absence of OCTN3 in humans, along with functional differences in OCT1 between humans and rodents, suggests that there are differences in the physiological and metabolic characteristics of carnitine across species

Early PARP-1 activation may delay apoptosis by suppressing Caspase-3, but prolonged NAD + depletion forces cells into AIF-dependent death [81]