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Webb et al

Clinical wins, safety setbacks, generics pressure, and aggressive IP maneuvering are reshaping the competitive landscape at record speed

Because neurodevelopment and vulnerability do not change abruptly at the 18-year threshold, similar caution is warranted in young adults

A prominent example of a specific mutation associated with obesity was the discovery that a four base-pair deletion in the melanocortin-4 receptor (MC4R) leads to obesity by inhibiting the leptin-melanocortin pathway [11]