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Introducing too much fluid too quickly can be dangerous, potentially leading to issues such as pulmonary edema or heart failure

In this trial, 195 adult patients exposed to JARDIANCE had an eGFR between 60 and 90 mL/min/1.73 m2, 91 adult patients exposed to JARDIANCE had an eGFR between 45 and 60 mL/min/1.73 m2, and 97 patients exposed to JARDIANCE had an eGFR between 30 and 45 mL/min/1.73 m2

doi: 10.1038/s42003-022-04242-7 30 HolstJJSchwartzTWKnuhtsenSJensenSLNielsenOV

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