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Risk factors include poor posture, lack of exercise, obesity, and underlying medical conditions

Pi-Sunyer, X, Astrup, A, Fujioka, K, et al

Unlike stable chemical compounds, peptides are vulnerable to heat, light, and pH changes

FIGURE 4 Results presented in Table 8 reveal that the highest absolute bioavailability is obtained for hydroxychalcone (10.54%), when calculated by the dose normalization method probably due to polar nature, while the other two markers being steroidal, the bioavailability was between 89%