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with the His at position 1 substituted and D-Ala at position 2) designed to confer metabolic stability against dipeptidyl peptidase IV (DPP-IV) cleavage and endopeptidase degradation without the albumin-binding Drug Affinity Complex (DAC) modification present in CJC-1295 With DAC

Post-reconstitution: Stable up to 30 days at 2-8C

In an experimental model of abdominal aortic aneurysm, topiramate markedly downregulated pro-inflammatory M1 macrophage activity, reduced the expression of TNF-, IL-1, and matrix metalloproteinase-9, and promoted a phenotypic shift of macrophages from M1 to M2, thereby mitigating pro-inflammatory activity and enhancing tissue repair processes (Attia et al., 2023)

Instead, its priced on a per unit basis