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Titration schedules in phase 3 trials of long acting insulin analogues incorporated individualization to allow the clinician to increase the dose to achieve optimal benefit without causing hypoglycaemia ( The oral obesity medications The oral GLP-1 based agents approved for obesity treatment deliver substantial weight loss

The future of combined insulin and GLP-1 therapy The line between insulin and GLP-1 therapy is becoming increasingly blurred, not because they are the same thing, but because they are increasingly used together

Faillie, JL, Yin, H, Yu, OHY, Herrero, A, Altwegg, R, Renoux, C, Azoulay, L

References 1.Lobstein T, Jackson-Leach R, Powis J, Brinsden H, Gray M