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Human studies in ulcerative colitis in 2002 and 2005 showed clinically meaningful results with an excellent safety profile

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Cumulative receptor engagement and therefore weight loss is determined by total weekly dose, not peak height

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Stroke 180 XinH.LiY.BullerB.KatakowskiM.ZhangY.WangX.et al (2012)

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Promptly, especially if it is persistent, worsening, or accompanied by other symptoms

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