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Symptoms of moderate disease can be managed with topical cyclosporine, nighttime eyelid taping, moisture goggles, prism glasses or selective ocular patching and moderate-dose oral steroid therapy

The 1st glutathione-interaction site should be frequently (although transiently) occupied by GSH at millimolar concentrations, whereas diverse non-glutathione disulfide substrates are far less abundant in vivo and should encounter the active site less frequently

(2002) Glutathione synthetase deficiency: is gamma-glutamylcysteine accumulation a way to cope with oxidative stress in cells with insufficient levels of glutathione

C., Potter W