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The broad prediction interval that includes the null value (OR = 1) indicates that the true effect in new settings could vary significantly
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Smoking is one of the biggest strains on the NHS, and has a massive impact on people across the nation, around 64,000 people die from smoking each year and in 2019 and 2020 statistics 1,991,183 people were hospitalised from smoking alone, which only increases year by year
This decrease in fertility in the offspring of treated female rats was not evident at an oral dose of 3 mg/kg/day (9 times the MRHD exposure based on AUC at 1 mg twice daily)
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