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Neuroinflammation has been shown to exacerbate the onset and progression of Alzheimers disease, and preclinical models demonstrate multiple direct effects of GLP-1 on attenuating neuroinflammation in the context of models of Alzheimers disease [15]

[4] [10] The phase 2 data demonstrated substantial weight loss up to 24.2% of body weight at the highest dose over 48 weeks alongside improvements in glycaemic control, making it one of the most efficacious agents studied to date in this class

This hormone is responsible for secreting insulin, as well, usually in response to consuming fats and carbohydrates

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