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For ex- ample, immortal time bias 30 may have been intro- duced as a new-user design was not used: patients with semaglutide prescriptions were first included regard- less of their comparator drug use history,and the com- parator group was selected from the remaining pa- tients prescribed the comparator drug (ie, the exposure status for the comparator group was conditioned on not being prescribed semaglutide after cohort entry)