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This review synthesizes recent progress across materials science, pharmacology, and clinical research to provide a cohesive framework linking nanocarrier composition, ligand engineering, stimuli-responsive release mechanisms, and theranostic functionality

We postulate that natural antibody repertoire defects precede emergence of beta cell-specific autoantibodies associated with and currently used to determine the risk of Type 1 diabetes progression. J

The most prevalent symptom is pain, which can manifest as sharp, dull, aching, or burning sensations