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However, similar to the antigen peptides identified by Caspi, SteTDR 917 cannot induce uveitis directly in mice, but it can synergize with IRBP, amplifying the activated state in a bystander manner, thereby exacerbating EAU (104)

8 Ex vivo studies further confirmed GAPs efficacy in reducing oxidative deoxyribonucleic acid (DNA) lesions and cyclobutene pyrimidine dimers under UVA and UVB irradiation, respectively, though these findings were limited by the small number of biomarkers evaluated