What a strong LMN includes: your diagnosis codes and clinical history, baseline BMI and weight trajectory, documented comorbidities (with cardiovascular disease, MASH, sleep apnea, and prediabetes being especially relevant for Wegovy appeals), a summary of prior treatments and why they were insufficient, supporting clinical evidence like the STEP trials for weight management, the SELECT trial for cardiovascular outcomes, and the ESSENCE trial for MASH, and a clear explanation of why Wegovy specifically, rather than just "a GLP-1," is the right choice
We chose to use low concentration of DTT rather than GSH/GR/NADPH to minimize interference by these GSH system components with oxidized versions of GLRX
Store all medicines out of the reach of children at all times
The number of Medicaid prescriptions and gross spending on GLP-1s have increased substantially since 2019 (Figure 2)