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To avoid the potential problem of overdosage, it is recommended that animals not be allowed free access to water immediately after each dose of desmopressin, especially if severe polydipsia and polyuria have redeveloped
Moreover, MN rats exhibited colonic structural injury, an increased Firmicutes-to-Bacteroidetes ratio, an elevated relative abundance of Allobaculum and Desulfovibrio , greater production of uremic toxin precursors, and reduced levels of SCFAs [136]
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Yuchi, Z., Lau, K
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