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It likely sequesters key binding partners such as ATF4 and C/EBP, preventing them from activating the CHAC1 gene ( CHAC1 promoter, allows for precise control of cell fate under prolonged ER stress ( The conservation of this regulatory axis is highlighted in other models
Am J Clin Nutr 77 , 13521360 (2003)
L'essai de Richie et al
The pathophysiological mechanism of hair loss induced by psychological stress may be associated with the upregulation of corticotropin-releasing hormone receptor (CRHR), adrenocorticotropin (ACTH), and acetylcholine (ACh) in the skin, which regulate immunity, promote cytokine secretion, and lead to the collapse of HF-IP (5658)
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