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This occurs because appetite returns to pre-treatment levels and the body's metabolic adaptations to weight loss persist, making weight maintenance challenging without continued intervention

[3] Probiotics are an adjunct, not a replacement, for GLP-1 medication

EBioMedicine 74(103739):103739 Gupta NA, Mells J, Dunham RM, Grakoui A, Handy J, Saxena NK, Anania FA (2010) Glucagon-like peptide-1 receptor is present on human hepatocytes and has a direct role in decreasing hepatic steatosis in vitro by modulating elements of the insulin signaling pathway

Forebrain CRF 1 modulates early-life stress-programmed cognitive deficits