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Previous GLP-1 agonist cardiovascular trials were conducted primarily in diabetic populations, leaving open the question of whether the heart benefits were mediated through glucose management or through direct cardiovascular effects of GLP-1 receptor activation

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Compounding is the process where a licensed pharmacist combines, mixes, or alters ingredients to create a medication tailored to the needs of an individual patient

As a result, 503B facilities often assign longer BUDs, sometimes 60-90 days or more, because they have the data to support those extended dates