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Growth hormone deficiency is associated with longer lifespan, and high levels of growth hormone and IGF-1 are linked to shorter lifespan, as seen in species like dogs where larger breeds with higher IGF-1 levels have shorter lifespans than smaller breeds 10s

It is more often discussed as a repair-focused compound because of its proposed effects on inflammation, tissue healing, angiogenesis, and mucosal protection

No Severe Effects in Controlled Observations: Intravenous infusion of up to 20 mg of BPC-157 in 2 healthy adults showed no adverse effects and was well-tolerated, with no measurable changes across heart, liver, kidney, thyroid, or blood glucose markers

Small errors in preparation, storage, or administration can undermine an otherwise well-designed protocol