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For example, a combination of NAC (1200 mg/day) and L-arginine (1600 mg/day) for 6 months to treat 8 oligo-menorrhoeic patients with PCOS helped restoring the menstrual function, as evidenced by the increased number of menstrual cycles, and significantly decreased the homeostatic model assessment (HOMA) index (144)

Consistently, this response was accompanied by a notable increase in SL levels in leaves, along with enhanced expression of SL biosynthetic genes, including VvCCD7 and VvCCD8 72

10.1186/1476-069X-13-43 36 SheikhI