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Although numerous topical and systemic therapeutic agents and also non-pharmacologic procedural treatments have been considered in melasma management, however, the commonly available therapeutic options have several limitations including the lack of sufficient clinical effectiveness, risk of relapse, and high rate of unwanted adverse drug reactions
New entrants such as Amgens MariTide and Viking Therapeutics VK2735 target differentiated dosing intervals or improved GI tolerability to carve share
It is sold legally in many regions strictly as a "research chemical" or "for laboratory use only." It is illegal to market it as a dietary supplement or human drug in the United States
The problem is not the food itself, it is the lack of variety
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