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Draw the required volume of bacteriostatic water into a sterile syringe

More recent evidence of its effectiveness in NDDs has led to guidelines and recommendations which emphasize behavioural management as the first line of intervention after medical reasons have been considered and treated or excluded [17] [20] [28] [37] - [43]

nonetheless, the lack of standardized techniques and the requirement for validation in larger, more varied patient cohorts continue to impede their therapeutic application