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A BMI of 27 or higher with at least one weight-related health condition, such as high blood pressure or type 2 diabetes

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GLP-1RAs aid in weight loss by regulating the gut-brain axis and interacting with leptin, while weight loss can alleviate the harmful effects of obesity on the body, particularly in knee OA, by reducing joint loading and inflammation

If you are dehydrated and you take a full dose of ibuprofen, your kidneys may be under significant stress