non glp-1 medications for weight loss Who Should Not Take Ozempic? Contraindications When Aren't a Good Fit The ABC's of GLP-1s: Benefits,

Shapiro DS, Renock S, Arrington E, Chiodo LA, Liu L

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How It Works Activates both GLP-1 and GIP receptors for a broader metabolic impact Reduces appetite and increases satiety through two hormonal pathways Enhances insulin sensitivity more aggressively than GLP-1 alone Supports reduction of visceral fat the deep abdominal fat most strongly associated with metabolic disease Improves blood sugar regulation through a dual insulin-stimulating mechanism Clinical Results In the SURMOUNT-1 trial, Tirzepatide produced average weight loss of up to 20% of body weight outperforming Semaglutide in head-to-head comparisons

Shadyro O, Samovich S, Edimecheva I