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It is thought that the secondary pathway by which AOD9604 causes fat loss, the pathway that is independent of beta-3-adrenergic receptor activation, may play a role in improving metabolic metrics even while it boosts fat loss- AOD9604 exhibits minimal side effects, high oral and excellent subcutaneous bioavailability in mice

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Biotin-tagged proteins can be enriched using avidin-coated resin before analysis, e.g., by immunoblot