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Year 2 HR 1.002 [0.9601.046])

Individual meal patterns should be developed based on personal preference and effectiveness

In contrast, in AMYRs bound to rAmy 15 or the pramlintide analogue, San385 16 , an Asn at the equivalent peptide position (N14 rAmy ) adopts an upward rotamer that is exposed to the solvent environment and forms a H-bond with the backbone of L291 ECL2 (Fig