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Conversely, another possibility is that a lower C4B copy number might protect the stability of the host microbiome to some extent by reducing the excessive clearance of beneficial microbes mediated by C4B

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Treatment with all uric acid concentrations caused a significant increase in protein carbonyl levels at 1 h compared with those in the control group, but 10 mg/dl uric acid dose resulted in a reduction compared with the other doses (2.5, 5 and 25 mg/dl uric acid) (Fig