What they found: 4,192 human genes change expression by 2 in response to GHK-Cu (31.2 % of the human genome) Of these 2,296 genes up-regulated , 1,896 down-regulated Pattern of changes: a rejuvenating signature, genes typically associated with ageing are down-regulated, regenerative genes up-regulated DNA repair , strong up-regulation of genes in BER, HR, NER pathways Mitochondrial biogenesis , increase in the number of mitochondria in cells Anti-apoptotic signal , protection against cell death Down-regulation of cancer signals , some oncogenes decreased Why it matters: This is the strongest evidence for the pleiotropic nature of GHK-Cu
This resulted in an estimated treatment difference of 41.7% after a year
A Stronger Immune System Vitamin C and zinc are central to immune health, working together to support the bodys response to pathogens and stress
Obesity is a well-recognized risk factor for HS, and excess adiposity contributes to mechanical friction, skin occlusion, and a proinflammatory state driven by adipokines and cytokines
