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This adhesion depends on the physicochemical properties of the inhaled therapeutics, which influence hydrogen bonding, hydrophobic interactions and electrostatic interactions 134

N-acetyl-L-cysteine (NAC) is the most common drug for neutralizing ROS to relieve OS and has been widely used in the respiratory and circulatory systems to relieve OS-related damage in cells [22,23,24]

A similar threshold effect was found for mean DBP during 1-12h at 75 mmHg, while no significance in 13-24h

Their results demonstrated that TRF significantly attenuated liver injury, decreased hepatic iron accumulation, and suppressed ferroptosis, thereby ameliorating NASH pathology