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The Lavis group made a seminal discovery that substituting the dialkylamino group with an azetidine group is a general method to significantly improve quantum yields of fluorophores 17

In other words, the system relies almost completely on the manufacturer following good quality control practices

The improvements in employment rates and work productivity across both absenteeism and presenteeism suggest that treatment with bimekizumab may allow patients living with PsA to reenter the employment market, indicating reduced burden of disease in individuals with a desire to return to work

2021;doi:10.1093/ehjcvp/pvab008 Lomuscio A, Belletti S, Battezzati PM, Lombardi F