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One 12-week randomized clinical trial found that subjects receiving 1mg daily lost an average of 2.6kg compared to 0.8kg in the placebo group

Hydroxocobalamin is the standard UK preparation, administered intramuscularly for conditions like pernicious anaemia and gastrointestinal malabsorption B12 acts as a cofactor in DNA synthesis, red blood cell formation, and nervous system function, supporting energy metabolism pathways Common side effects include injection site reactions, mild gastrointestinal upset, and temporary urine discolouration, with serious reactions being rare NHS access requires GP assessment with blood tests

Additionally, do not use it if you have a known allergy to semaglutide

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