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After plateau, participants in clinical trials showed minimal regain (less than 2 lb) while continuing treatment through week 48

For instance, glucosylceramide synthase inhibitors can mitigate neuroinflammation by interrupting immunometabolic pathways in pathogenic astrocytes [304]

The results showed a 7% increase in deceased donors, but a significant 29% drop in living donors overall, driven by a reduction in altruistic donations (meaning organs donated to non-family members)