glp-1 weight loss journey 2024 in Review: The Rise of Medications for GLP-1 Lifestyle Friendly - Splenda®

They can be appropriate in limited situations under specific rules

Oral studies use 500-1500 mg daily

Bunck et al., 2009

For tirzepatide (Zepbound) Jastreboff and colleagues reported in the New England Journal of Medicine in 2022 that at maximal doses, the percent of individuals reporting side effects were as follows: Nausea 31.0% Diarrhea 23.0% Vomiting 12.2% Constipation 11.7% Bettge and colleagues conducted a study published in Diabetes, Obesity, and Metabolism in 2017 that showed that individuals who were taking metformin while taking a GLP-1 were more likely to have side effects, especially nausea and vomiting