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In the future, with the development of long-acting PYY analogs, selective Y receptor modulators, and gut L-cell regulatory strategies, combined with in-depth mechanistic studies and large-scale clinical trials, PYY is expected to become a novel therapeutic target for insulin resistance and related metabolic disorders

Daniel Chille If you look at the blue zones, the two things that really stood out to me that were kind of underpinned or representative of each blue zone population was community and movement

Pillinger T, McCutcheon RA, Vano L, Mizuno Y, Arumuham A, Hindley G, et al