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Mitochondrial-mediated ROS cause oxidative damage to cellular structures, particularly mitochondrial DNA, somatic mutations, genome instability, inactivation of tumor suppressor genes, alterations in metabolic and signaling pathways with simultaneous activation of compensatory antioxidant mechanisms, all of which contribute to cell transformation and thus promote various types of cancer [42]

Weight-loss medications like semaglutide have skyrocketed in popularity in recent years, but could have dangerous side effects and should be a last resort, according to the celebrity personal trainer Jillian Michaels

Primary outcomes were changes in HbA1c, fasting and post-OGTT glucose after 12 weeks

China has the largest population of patients with T2D in a single country [1]