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Available from: Astrup A, Rssner S, Van Gaal L, et al

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Preclinical studies with a long-acting polyethylene glycosylated (PEGylated) FGF21 analog, B1344, in non-human primates with non-alcoholic liver disease demonstrated reduction of steatosis, attenuation of inflammation and fibrosis, and reduced hepatocyte injury after 11 weeks of therapy as assessed by analyzing liver biopsies [36]