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Xenobiotic conjugation and detoxification GSH is also crucial for detoxification of xenobiotics (95, 199, 334)

But the glucagon-driven metabolic improvements, including better lipid profiles, reduced inflammation markers, and improved insulin sensitivity, suggest benefits beyond what weight loss alone would explain

While tirzepatide's primary indications focus on metabolic health, its effects on weight loss and glycemic control may have secondary benefits for various obesity- and diabetes-related complications, though cardiovascular outcome trials are still ongoing

[DOI] [PubMed] [Google Scholar] 232.Heid M.E., Keyel P.A., Kamga C., Shiva S., Watkins S.C., Salter R.D