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Vital signs, particularly heart rate and blood pressure, are checked regularly, as GLP-1 agonists can slightly increase resting heart rate while beneficially lowering blood pressure

Early treatment of existing macular edema or proliferative changes before starting the medication can reduce your risk of vision-threatening progression

It has been engineered to bind more strongly to albumin (a protein in the blood), which means it stays active in the body for much longer than liraglutide

Those with a history of medullary thyroid carcinoma (MTC) or multiple endocrine neoplasia type 2 (MEN2) should avoid GLP-1 drugs due to theoretical risk based on animal studies, not human evidence