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These transcriptional changes are especially prominent in the PFC and cerebellum with hundreds of affected genes

Hydrogen peroxide-dependent 4-t-butylphenol hydroxylation by tyrosinasea new catalytic activity

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ROS participate in this process by modulating signal transduction pathways that promote tyrosine phosphorylation, a key event in sperm activation ( In addition to lipid peroxidation, oxidative stress induces protein oxidation, which affects the function of key proteins involved in sperm motility and structure ( Oxidative stress in spermatozoa can originate from both internal and external sources