In adults, symptoms may include: chronic diarrhea that does not get better with medication foul-smelling, greasy, pale stool gassiness recurring abdominal bloating weight loss fatigue infertility, lack of menstruation bone or joint pain depression, irritability, or mood changes neurological problems, including weakness, poor balance, seizures, headaches, or numbness or tingling in the legs itchy, painful skin rash (dermatitis herpetiformis) tooth discoloration or loss of enamel, sores on lips or tongue other signs of vitamin deficiency, such as scaly skin or hyperkeratosis (from lack of vitamin A), or bleeding gums or bruising easily (from lack of vitamin K)
Most users report that nighttime injection reduces daytime diarrhea episodes by allowing the initial receptor activation surge to pass overnight
Combined vemurafenib and cobimetinib in BRAF-mutated melanoma
Bacteriostatic water for injection (BWFI) is a sterile, nonpyrogenic aqueous solution containing 0.9% (9 mg/mL) benzyl alcohol as a preservative