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It is generally safe for short-term use

Free Radical Biology and Medicine, 39, 34554

Allergy, Asthma & Clinical Immunology (2013)

Its normal to have some homocysteine in your blood, but elevated levels can cause health problems like coronary artery disease, heart attack, stroke, and cognitive decline.18 B vitamins can break homocysteine down into chemicals your body needs, but not effectively if you have a vitamin deficiency or a defect in the gene ( MTHFR ) responsible for processing the amino acid.19 TMG, however, also breaks down homocysteine into the essential antioxidant amino acid methionine, necessary for making protein in your body and regulating metabolic processes20 21 so it effectively rehabilitates a delinquent compound into a contributing member to your biochemistry