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Journal of Biomaterials Science, Polymer Edition , 19(8), 969-988

Kidney effects of Glucagon-Like Peptide 1 (GLP1): from molecular foundations to a pharmacophysiological perspective DOI: 10.1590/2175-8239-JBN-2024-0101pt Graphical Abstract Click to view Abstract GLP1 receptor agonists (GLP1-RAs) are drugs that mimic the effects of the incretin hormone GLP1 and were initially introduced in medicine for the treatment of diabetes in 2005 and for obesity in 2014

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Ferroptosis is essentially the outcome of oxidative stress caused by iron overload, with Fe 2+ and PUFAs and lipid peroxidation the leading cause of ferroptotic cell death [101, 102]