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Asbestosisnot asbestos exposurehas been invoked as the primary risk factor for lung cancer as recently as 2014 [38], and Cagle [51] commented that Unless and until a better marker comes along, the only consistently reliable marker for an asbestos-related lung cancer is asbestosis, especially in asbestos workers who are also tobacco smokers. We consider that in some instances, a clinical-radiologic diagnosis of early/mild asbestosis cannot be made with consistency or reliability, and may be the subject of dispute among respiratory physicians and radiologists, because of the following disagreements: Dispute as to whether there is genuine interstitial fibrosis, even in high-resolution CT scans [132], or whether any changes are related to associated pleural fibrosis

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