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Receptor Specificity & Selectivity The defining pharmacological difference between ipamorelin and GHRP-6 is receptor selectivity

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The first studies evaluating the effects of GLP-1 and exendin-4 in neuronal cells demonstrated their ability to promote neurite outgrowth (a similar effect to that observed with the neurotrophic nerve growth factor) and to protect cultured neurons against glutamate-induced apoptosis [33]