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The production of Lac-Phe autonomously increases in macrophages and intestinal epithelial cells in a cytosolic non-specific dipeptidase 2 (CNDP2)-dependent manner, where CNDP2 is a major Lac-Phe biosynthetic enzyme (Xiao et al., 2023)

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Ozempic (Semaglutide for Type 2 Diabetes) According to FDA prescribing information, Ozempic is indicated for adults with type 2 diabetes to improve glycemic control alongside diet and exercise