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An additional experiment conducted during this study showed that by treating 3T3-L1 adipocytes with NAC (600 M), a methylglyoxal impairment in insulin signalling was relieved, as shown by decreased insulin-induced insulin receptor substrate-1 tyrosine phosphorylation and decreased activity of phosphatidylinositol 3-kinase (66)

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Reductive carboxylation supports redox homeostasis during anchorage-independent growth

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Endogenous glucagon-like peptide-1 suppresses high-fat food intake by reducing synaptic drive onto mesolimbic dopamine neurons

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