glp-1 drugs and fertility may improve by boosting metabolic health: Study GLP-1 Drugs And Erectile Dysfunction:

A woman is born with every egg she will ever have, and a sperm cell takes about three months to develop

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(PubMed) Wilson SM, Bivins BN, Russell KA, Bailey LB

Specifically, the variants G247Vfs*6 and G283R exhibit embryonic lethality upon exposure to -BB at mM concentrations, closely mimicking the response observed in the knockout alleles